Document Detail

Galacto-oligosaccharide production using microbial beta-galactosidase: current state and perspectives.
MedLine Citation:
PMID:  19943044     Owner:  NLM     Status:  MEDLINE    
Galacto-oligosaccharides have become the focus of a great deal of attention in the field of functional foods, owing to their known health benefits and potential to improve the quality of many foods. Because of these properties, they are currently used as low-calorie sweeteners in fermented milk products, confectioneries, breads, and beverages. In this article, the characterization and product inhibition of many microbial beta-galactosidases with transgalactosylation activities, their galacto-oligosaccharide production from lactose, and the application of galacto-oligosaccharides are reviewed. A method for increasing galacto-oligosaccharide production by reducing product inhibition properties via the immobilization and structure modification of the enzymes is also introduced herein.
Ah-Reum Park; Deok-Kun Oh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-11-27
Journal Detail:
Title:  Applied microbiology and biotechnology     Volume:  85     ISSN:  1432-0614     ISO Abbreviation:  Appl. Microbiol. Biotechnol.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-21     Completed Date:  2010-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406612     Medline TA:  Appl Microbiol Biotechnol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1279-86     Citation Subset:  IM    
Department of Bioscience and Biotechnology, Konkuk University, Seoul 143-701, Republic of Korea.
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MeSH Terms
Bacteria / enzymology
Enzyme Inhibitors / metabolism,  pharmacokinetics
Fungi / enzymology
Galactose / metabolism,  pharmacology
Glucose / metabolism,  pharmacology
Lactose / metabolism*
Oligosaccharides / chemistry,  metabolism*
beta-Galactosidase / antagonists & inhibitors,  metabolism*
Reg. No./Substance:
0/Enzyme Inhibitors; 0/Oligosaccharides; 26566-61-0/Galactose; 50-99-7/Glucose; 63-42-3/Lactose; EC

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