| Gait disturbance in Alzheimer's disease: a clinical study. | |
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MedLine Citation:
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PMID: 8831878 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gait disturbance is common in patients with Alzheimer's disease (AD). The aim of this study was to analyse the clinical gait syndromes of patients with AD using Nutt's classification. Fifty-five patients who satisfied the NINCDS-ADRDA criteria for probable AD and 55 controls were recruited from a geriatric and a psychogeriatric unit. Patients with classical musculoskeletal or neurological syndromes causing gait disturbance were excluded. A standardized neurological examination was carried out in all subjects. Twenty-two (40%) patients and ten (18%) controls had a higher level gait disorder (p < 0.01). The pattern of gait disturbance in AD patients varied according to the stage of the disease. Cautious gait was the commonest gait disorder in AD patients with mild dementia, while frontal gait disorder was the commonest disturbance in patients with severe dementia. The prevalence of frontal release signs (gegenhalten or any primitive reflex) was highest among patients with frontal gait disorder. |
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Authors:
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S T O'Keeffe; H Kazeem; R M Philpott; J R Playfer; M Gosney; M Lye |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Age and ageing Volume: 25 ISSN: 0002-0729 ISO Abbreviation: Age Ageing Publication Date: 1996 Jul |
Date Detail:
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Created Date: 1997-01-16 Completed Date: 1997-01-16 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0375655 Medline TA: Age Ageing Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 313-6 Citation Subset: IM |
Affiliation:
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Department of Geriatric Medicine, Royal Liverpool University Hospital. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Activities of Daily Living
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classification Aged Aged, 80 and over Alzheimer Disease / classification, diagnosis*, physiopathology Female Frontal Lobe / physiopathology Gait* / physiology Humans Male Neurologic Examination Postural Balance / physiology Reflex, Abnormal / physiology Risk Factors |
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