Document Detail


Gadolinium-enhanced MRI of the abnormal prostate.
MedLine Citation:
PMID:  7694028     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective study of the use of a low osmolar gadolinium-based intravenous contrast material for MRI of the abnormal prostate was performed. Eight patients scheduled for prostatectomy, six with prostate cancer and two with benign prostatic hyperplasia (BPH), were imaged preoperatively on a 1.5 T system using a pelvic coil array and employing Gadodiamide (0.3 mmol/kg). T2-weighted fast-spin echo (FSE) imaging was also performed in the same axial planes employed for gadolinium-enhanced studies. Detailed pathologic correlation was performed for the six patients with carcinoma. While regions of BPH and cancer enhanced to a similar degree following intravenous contrast agent, BPH enhancement was more heterogeneous than cancer. No advantages in detecting prostate cancer, in differentiating cancer from BPH or normal prostatic tissue, or in assessing extra-prostatic spread of cancer were observed for the contrast-enhanced studies compared to T2-weighted FSE imaging.
Authors:
F G Sommer; H V Nghiem; R Herfkens; J McNeal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Magnetic resonance imaging     Volume:  11     ISSN:  0730-725X     ISO Abbreviation:  Magn Reson Imaging     Publication Date:  1993  
Date Detail:
Created Date:  1993-12-16     Completed Date:  1993-12-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8214883     Medline TA:  Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  941-8     Citation Subset:  IM    
Affiliation:
Department of Radiology, Stanford University School of Medicine, CA 94305-5105.
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MeSH Terms
Descriptor/Qualifier:
Aged
Contrast Media
Gadolinium DTPA*
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Organometallic Compounds / diagnostic use*
Pentetic Acid / analogs & derivatives*,  diagnostic use
Prospective Studies
Prostatic Hyperplasia / diagnosis*
Prostatic Neoplasms / diagnosis*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 122795-43-1/gadodiamide; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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