Document Detail


Gadolinium-DTPA enhanced echoplanar MR imaging of the liver: preliminary observations.
MedLine Citation:
PMID:  8761389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study describes our preliminary experience with dynamic gadopentetate dimeglumine enhanced echoplaner MR imaging (EPI) in fifteen patients with focal liver lesions. Lesion diagnosis was established by histology (n = 3) or typical imaging characteristics (exclusive of the EPI study) combined with clinical follow up (n = 12). Dynamic gadopentetate dimeglumine (0.1 mmol/kg) enhanced MR imaging was performed on a commercially available 1.5 T EPI equipped MR system using a single-excitation fat-suppressed inversion recovery pulse sequence. The choice of an IR sequence allowed nulling of the lesion signal by varying T1 prior to enhancement creating the optimal conditions for qualitative inspection of the enhancement profile. Intershot delay (defined as TR) ranged from 1-5s. Image analysis was performed qualitatively by two radiologists. Benign and malignant lesions displayed temporal enhancement profiles compatible with characteristic findings expected with conventional imaging modalities. Further refinements in our technique and expanded system capabilities will allow dynamic imaging of the entire liver with improved temporal resolution over conventional sequences.
Authors:
D A Gervais; S Saini; P F Hahn; P Reimer; M A Goldberg; R Weiskoff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical radiology     Volume:  51     ISSN:  0009-9260     ISO Abbreviation:  Clin Radiol     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-10-01     Completed Date:  1996-10-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  545-9     Citation Subset:  IM    
Affiliation:
Department of Radiology, Massachusetts General Hospital, Boston 02114, USA.
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MeSH Terms
Descriptor/Qualifier:
Contrast Media*
Echo-Planar Imaging / methods*
Gadolinium DTPA
Humans
Liver Diseases / diagnosis*
Organometallic Compounds / diagnostic use*
Pentetic Acid / analogs & derivatives*,  diagnostic use
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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