| Gadobenate dimeglumine-enhanced liver MR imaging in cirrhotic patients: Quantitative and qualitative comparison of 1-hour and 3-hour delayed images. | |
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MedLine Citation:
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PMID: 21448954 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: To compare the image quality and diagnostic performance of 1- and 3-h delayed-phase MR images (DPIs) after gadobenate dimeglumine injection in detecting small hepatocellular carcinomas (HCCs) in cirrhotic patients. MATERIALS AND METHODS: Relative enhancement of the liver (RE(liver) ) and HCC (RE(HCC) ) and liver-to-lesion contrast-to-noise ratio (CNR) of HCC were measured quantitatively on 1- and 3-h DPIs in 65 patients with 88 HCCs. For qualitative analysis, two radiologists independently evaluated three image sets in 19 patients with 25 HCCs ≤2 cm and in 16 controls without HCCs: conventional liver MR without DPI (set A), adding 1-h DPI (set B), and adding 3-h DPI (set C), using a 5-point scale for diagnosing small HCCs. Diagnostic performance for small HCCs was analyzed using the alternative free-response receiver operating characteristic method. RESULTS: Mean RE(liver) (P = 0.013) and RE(HCC) (P < 0.001) were significantly higher on 1-h than on 3-h DPI, whereas CNR was significantly higher on 3-h than on 1-h DPI (P = 0.001). Observer-averaged figure of merit (FOM) was significantly higher for set C than for set A (0.942 versus 0.883; P = 0.013). CONCLUSION: In cirrhotic patients, 3-h DPI provides a higher liver-to-lesion contrast and a better diagnostic performance for small HCCs than 1-h DPI. J. Magn. Reson. Imaging 2011;33:889-897. © 2011 Wiley-Liss, Inc. |
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Authors:
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Woo Kyoung Jeong; Jae Ho Byun; Seung Soo Lee; Hyung Jin Won; Kyoung Won Kim; Yong Moon Shin; Pyo Nyun Kim; Moon-Gyu Lee |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 33 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 889-97 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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