Document Detail


Ga-67 citrate scintigraphy for the early detection of radiation pneumonitis.
MedLine Citation:
PMID:  1544257     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate the usefulness of Ga-67 citrate scintigraphy in the early detection of radiation pneumonitis, scintigrams from 103 patients who were treated with radiation therapy for lung cancer were retrospectively analyzed with regard to abnormal Ga-67 uptake after radiation therapy in sites other than the original or recurrent tumors. Sixteen (20%) of the 80 asymptomatic cases showed positive Ga-67 scintigrams. All of the other 23 symptomatic cases showed positive Ga-67 scintigrams. Thirteen (57%) of these 23 cases had negative chest radiographs although their Ga-67 scintigrams were positive. Detection of radiation pneumonitis by Ga-67 scintigraphy was significantly earlier than that possible by chest radiography (P less than 0.01). These data suggest that Ga-67 scintigraphy is more useful and sensitive than chest radiography for the early detection of radiation pneumonitis.
Authors:
M Kataoka; M Kawamura; H Itoh; K Hamamoto
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical nuclear medicine     Volume:  17     ISSN:  0363-9762     ISO Abbreviation:  Clin Nucl Med     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-04-10     Completed Date:  1992-04-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7611109     Medline TA:  Clin Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  27-31     Citation Subset:  IM    
Affiliation:
Department of Radiology, Ehime University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Citrates / diagnostic use*
Citric Acid
Female
Gallium / diagnostic use
Gallium Radioisotopes / diagnostic use*
Humans
Lung / radiography,  radionuclide imaging*
Lung Neoplasms / radiotherapy
Male
Pneumonia / radiography,  radionuclide imaging*
Radiation Injuries / radiography,  radionuclide imaging*
Radiotherapy / adverse effects*
Time Factors
Chemical
Reg. No./Substance:
0/Citrates; 0/Gallium Radioisotopes; 7440-55-3/Gallium; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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