Document Detail


GP IIb/IIIa inhibitors in coronary artery disease management: what the latest trials tell us.
MedLine Citation:
PMID:  11765119     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent clinical trials have refined our understanding of how the glycoprotein (GP) IIb/IIIa inhibitors should best be used. These trials examined whether there are clinical differences between agents, whether empiric use of GP IIb/IIIa inhibitors in acute coronary syndromes is justified, and whether these drugs might allow for early invasive management in acute coronary syndromes.
Authors:
D P Chew; D J Moliterno
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Cleveland Clinic journal of medicine     Volume:  68     ISSN:  0891-1150     ISO Abbreviation:  Cleve Clin J Med     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-17     Completed Date:  2002-01-03     Revised Date:  2013-05-24    
Medline Journal Info:
Nlm Unique ID:  8703441     Medline TA:  Cleve Clin J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1017-23     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, OH 44195, USA.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Angina, Unstable / drug therapy
Angioplasty, Balloon, Coronary
Antibodies, Monoclonal / administration & dosage,  therapeutic use
Anticoagulants / administration & dosage,  therapeutic use*
Atherectomy
Clinical Trials as Topic*
Coronary Disease / drug therapy*,  surgery,  therapy
Fibrinolytic Agents / administration & dosage,  therapeutic use*
Humans
Immunoglobulin Fab Fragments / administration & dosage,  therapeutic use
Myocardial Infarction / drug therapy
Peptides / administration & dosage,  therapeutic use
Placebos
Platelet Aggregation Inhibitors / administration & dosage,  therapeutic use*
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
Stents
Syndrome
Time Factors
Treatment Outcome
Troponin T / blood
Tyrosine / administration & dosage,  analogs & derivatives*,  therapeutic use
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Anticoagulants; 0/Fibrinolytic Agents; 0/Immunoglobulin Fab Fragments; 0/Peptides; 0/Placebos; 0/Platelet Aggregation Inhibitors; 0/Platelet Glycoprotein GPIIb-IIIa Complex; 0/Troponin T; 0/eptifibatide; 144494-65-5/tirofiban; 55520-40-6/Tyrosine; X85G7936GV/abciximab

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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