Document Detail


GH response to GH-releasing factor in dementia and its relation with TSH response to TSH-releasing factor.
MedLine Citation:
PMID:  1759034     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have studied the GH response to GH-releasing factor (GRF) and the TSH response to TSH-releasing factor (TRH) in two groups or patients with dementia. A group of 28 patients with Alzheimer's disease (AD) and another group of 28 patients with dementia of vascular origin (VD). The GH response to GRF exhibited no difference between AD and VD patients (12.2 +/- 10.85 micrograms/L vs. 9.96 +/- 9.9) and there was no correlation with GH response to GRF and sex, stage of the disease and cerebral atrophy. The number of cases with exaggerated, normal or without response were similar in AD or VD patients. The TSH response to TRH exhibited no difference between AD and VD patients (9.18 +/- 4.93 mU/ml vs. 10.35 +/- 8.81). There was no correlation with TSH response to TRH and sex, stage of the disease, cerebral atrophy and response of GH to GRF. The number of cases with exaggerated, normal or without response was similar in AD or VD patients.
Authors:
J M Gómez Sáez; M Aguilar Barberá
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Recenti progressi in medicina     Volume:  82     ISSN:  0034-1193     ISO Abbreviation:  Recenti Prog Med     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-01-31     Completed Date:  1992-01-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401271     Medline TA:  Recenti Prog Med     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  514-6     Citation Subset:  IM    
Affiliation:
Endocrinology Service, Hospital de Bellvitge, Barcelona, Spain.
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MeSH Terms
Descriptor/Qualifier:
Aged
Alzheimer Disease / blood,  diagnosis,  physiopathology
Dementia / blood,  diagnosis*,  physiopathology
Dementia, Vascular / blood,  diagnosis,  physiopathology
Female
Growth Hormone / blood*
Growth Hormone-Releasing Hormone / diagnostic use*
Humans
Male
Middle Aged
Thyrotropin / blood*
Thyrotropin-Releasing Hormone / diagnostic use*
Chemical
Reg. No./Substance:
24305-27-9/Thyrotropin-Releasing Hormone; 9002-71-5/Thyrotropin; 9002-72-6/Growth Hormone; 9034-39-3/Growth Hormone-Releasing Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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