| G-cell density in the antral mucosa: a feasibility study. | |
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MedLine Citation:
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PMID: 9147077 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this work a new method for gastrin-secreting cell (G-cell) density measurement was employed in order to test the hypothesis that G-cell density of the antral mucosa can be estimated with an acceptable degree of error. The zone of antral mucosa where most G-cells are located was demarcated, its area was measured and the G-cells within this area were counted. The variation in the e error of the estimate according to normal distribution theory, and the size of the sampling expected to yield G-cell density values with a given error were assessed. Our data indicate that a very large surface of the G-cell zone should be explored in order to estimate G-cell density with an acceptable degree of error. G-cell density measurement appears not to be feasible on biopsy specimens or, for routine diagnosis, on gastrectomy specimens. |
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Authors:
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C Pesce; R Rossi; E Lenti; R Tanzi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Histopathology Volume: 30 ISSN: 0309-0167 ISO Abbreviation: Histopathology Publication Date: 1997 Apr |
Date Detail:
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Created Date: 1997-08-14 Completed Date: 1997-08-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7704136 Medline TA: Histopathology Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 315-8 Citation Subset: IM |
Affiliation:
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Cattedra di Istituzioni di Anatomia e Istologia Patologica. Università di Genova, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cell Count / methods* Feasibility Studies Gastric Mucosa / cytology* Gastrins / secretion Humans Mathematics Pyloric Antrum / cytology*, secretion Sample Size Stomach Diseases / diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Gastrins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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