Document Detail

G-cell density in the antral mucosa: a feasibility study.
MedLine Citation:
PMID:  9147077     Owner:  NLM     Status:  MEDLINE    
In this work a new method for gastrin-secreting cell (G-cell) density measurement was employed in order to test the hypothesis that G-cell density of the antral mucosa can be estimated with an acceptable degree of error. The zone of antral mucosa where most G-cells are located was demarcated, its area was measured and the G-cells within this area were counted. The variation in the e error of the estimate according to normal distribution theory, and the size of the sampling expected to yield G-cell density values with a given error were assessed. Our data indicate that a very large surface of the G-cell zone should be explored in order to estimate G-cell density with an acceptable degree of error. G-cell density measurement appears not to be feasible on biopsy specimens or, for routine diagnosis, on gastrectomy specimens.
C Pesce; R Rossi; E Lenti; R Tanzi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Histopathology     Volume:  30     ISSN:  0309-0167     ISO Abbreviation:  Histopathology     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-08-14     Completed Date:  1997-08-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704136     Medline TA:  Histopathology     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  315-8     Citation Subset:  IM    
Cattedra di Istituzioni di Anatomia e Istologia Patologica. Università di Genova, Italy.
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MeSH Terms
Cell Count / methods*
Feasibility Studies
Gastric Mucosa / cytology*
Gastrins / secretion
Pyloric Antrum / cytology*,  secretion
Sample Size
Stomach Diseases / diagnosis
Reg. No./Substance:

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