Document Detail

Future recovery of the normal menstrual cycle in adolescent patients with secondary amenorrhea.
MedLine Citation:
PMID:  19527397     Owner:  NLM     Status:  MEDLINE    
AIMS: We attempted to determine the future recovery rate of normal menstrual cycles in adolescents with secondary amenorrhea. We also attempted to determine the difference in recovery rate between patients with and without etiological factors for amenorrhea, and between those with first- and second-degree secondary amenorrhea. METHODS: We conducted questionnaire-based analysis of 35 patients with adolescent secondary amenorrhea. When the patients were over 20 years old, we obtained information as to the present menstruation status and the history of pregnancy. RESULTS: Seventy-four percent of patients recovered their normal menstrual cycles after the age of 20. The recovery rate was significantly higher in patients with etiological factors (93%) than in those without (60%: P = 0.02). There was a trend towards a higher recovery rate in those with second-degree compared with first-degree amenorrhea, but this was not statistically significant. CONCLUSIONS: Three-quarters of adolescent patients with secondary amenorrhea recovered their normal menstrual cycles. The initial presence of etiological factors for amenorrhea raised the recovery rate. This data provides useful prognostic information for health providers taking care of adolescents with secondary amenorrhea.
Yukako Morimatsu; Shigeki Matsubara; Takashi Watanabe; Yuko Hashimoto; Tomoe Matsui; Kyoko Asada; Mitsuaki Suzuki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  35     ISSN:  1341-8076     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-16     Completed Date:  2009-08-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  545-50     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Jichi Medical University, Shimotsuke, Tochigi, Japan.
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MeSH Terms
Amenorrhea / blood,  etiology*,  therapy*
Estradiol / blood
Follicle Stimulating Hormone / blood
Follow-Up Studies
Luteinizing Hormone / blood
Polycystic Ovary Syndrome / diagnosis
Stress, Psychological / complications
Weight Loss
Reg. No./Substance:
50-28-2/Estradiol; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

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