| Future perspectives on neuroendocrine tumors. | |
| | |
MedLine Citation:
|
PMID: 21327890 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
In the last 30 years the incidence and prevalence of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased substantially. This could be partly due to improvements in diagnostic imaging, which lead to the incidental diagnosis of asymptomatic cases. However, despite these improvements, patients typically experience long delays before they are diagnosed. In this review, we discuss both the limitations and advances in our understanding of the pathogenesis, molecular and cellular biology, diagnosis, classification, staging, and treatment of GEP-NETs in order to identify which factors could be contributing to the delay in diagnosis and timely treatment of these patients. Within this context, the results from the most relevant clinical trials the available targeted therapies for the treatment of GEP-NETs, such as the "RAD001 in Advanced Neuroendocrine Tumors," will be discussed. |
| | |
Authors:
|
Daniel Castellano; Ramón Salazar; Eric Raymond |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-2-17 |
Journal Detail:
|
Title: Cancer metastasis reviews Volume: - ISSN: 1573-7233 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-2-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8605731 Medline TA: Cancer Metastasis Rev Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain, cdanicas@hotmail.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Subtilase Genes Diversity in the Biogas Digester Microbiota.
Next Document: Multiple Mirror-Image Peripheral Arterial Aneurysms in Kawasaki Disease.