| Future directions in esophageal motility and function - new technology and methodology. | |
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MedLine Citation:
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PMID: 22248108 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background Symptom based diagnosis is not reliable in patients with swallowing problems, heartburn, and other dyspeptic complaints. The aim of investigation is to provide clinically relevant measurements of gastrointestinal structure and function that explain the cause of symptoms, identify pathology, and guide effective management. Current practice rarely meets these ideals. Purpose This review considers recent advances in technology such as high-resolution manometry (HRM) with esophageal pressure topography (EPT), HRM with impedance, high frequency ultrasound, and endoscopic functional luminal impedance planimetry (Endo-FLIP) that provide new opportunities to identify the pathophysiologic basis of esophageal symptoms and disease. As experience with these new devices increases researchers are developing new methodologies that maximize their utility in clinical practice. For example, application of HRM to assess motility and function during and after a test meal can identify the causes of swallowing problems, reflux and other postprandial symptoms and intra-operative application of Endo-FLIP may help surgeons perform antireflux surgery. These examples illustrate the potential of physiologic measurement to direct rational and effective clinical management for individual patients. |
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Authors:
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M Fox; R Sweis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society Volume: 24 Suppl 1 ISSN: 1365-2982 ISO Abbreviation: Neurogastroenterol. Motil. Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-01-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9432572 Medline TA: Neurogastroenterol Motil Country: England |
Other Details:
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Languages: eng Pagination: 48-56 Citation Subset: IM |
Copyright Information:
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© 2012 Blackwell Publishing Ltd. |
Affiliation:
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NIHR Biomedical Research Unit, Nottingham Digestive Diseases Centre, Queen's Medical Centre, Nottingham, UK Oesophageal laboratory, Guy's and St. Thomas' Hospital NHS Foundation Trust, London, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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