Document Detail


Future approaches in periodontal regeneration: gene therapy, stem cells, and RNA interference.
MedLine Citation:
PMID:  20103477     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Periodontal disease is a major public health issue and the development of effective therapies to treat the disease and regenerate periodontal tissue is an important goal of today's medicine. This article highlights recent scientific advancements in gene therapy, stem cell biology, and RNA interference with the intent of identifying their potential in periodontal tissue regeneration. Results from basic research, preclinical, and clinical studies indicate that these fields of research may soon contribute to more effective regenerative therapies for periodontal disease.
Authors:
Giuseppe Intini
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Dental clinics of North America     Volume:  54     ISSN:  1558-0512     ISO Abbreviation:  Dent. Clin. North Am.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-27     Completed Date:  2010-02-24     Revised Date:  2010-04-12    
Medline Journal Info:
Nlm Unique ID:  0217440     Medline TA:  Dent Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-55     Citation Subset:  D; IM    
Affiliation:
Department of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Avenue, REB 513, Boston, MA 02115, USA. giuseppe_intini@hsdm.harvard.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone Regeneration / genetics
Gene Therapy*
Humans
Osteogenesis / genetics
Periodontal Attachment Loss / surgery,  therapy*
RNA Interference*
Regeneration* / genetics,  physiology
Stem Cell Transplantation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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