Document Detail


Future of molecular testing for red blood cell antigens.
MedLine Citation:
PMID:  20513560     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
When one looks at the field of molecular pathology or transplantation, it is evident that molecular biology has made a positive impact on medicine. However, the progress in transfusion medicine has been slower and more cautious than in other areas of the clinical laboratory. To understand where the field may go in the next 10 years requires that the reader understand what technology is available now. Therefore, this article discusses the current state of the art for red-cell genotyping and newer, ever-evolving molecular technologies. Because it is impossible to present all of the molecular techniques and their variations in this article, the author selects a group of methodologies to review and speculates where the field of molecular immunohematology may be in 2020.
Authors:
Joann M Moulds
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics in laboratory medicine     Volume:  30     ISSN:  1557-9832     ISO Abbreviation:  Clin. Lab. Med.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-01     Completed Date:  2010-09-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100174     Medline TA:  Clin Lab Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  419-29     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Affiliation:
Clinical Immunogenetics, LifeShare Blood Centers, 8910 Linwood Avenue, Shreveport, LA 71106, USA. jmmoulds@lifeshare.org
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MeSH Terms
Descriptor/Qualifier:
Automation, Laboratory
Blood Group Antigens / genetics*
Erythrocytes / cytology,  immunology*
Genotype
High-Throughput Screening Assays
Humans
Molecular Diagnostic Techniques / methods*
Oligonucleotide Array Sequence Analysis / methods*
Polymorphism, Single Nucleotide
Chemical
Reg. No./Substance:
0/Blood Group Antigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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