| The future of discovery chemistry: quo vadis? Academic to industrial--the maturation of medicinal chemistry to chemical biology. | |
| | |
MedLine Citation:
|
PMID: 20149893 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
At Roche, we set out to think about the future role of medicinal chemistry in drug discovery in a project involving both Roche internal stakeholders and external experts in drug discovery chemistry. To derive a coherent strategy, selected scientists were asked to take extreme positions and to derive two orthogonal strategic options: chemistry as the traditional mainstream science and chemistry as the central entrepreneurial science. We believe today's role of medicinal chemistry in industry has remained too narrow. To provide the innovation that industry requires, medicinal chemistry must play its part and diversify at pace with our increasing understanding of chemical biology and network pharmacology. |
| | |
Authors:
|
Torsten Hoffmann; Cheryl Bishop |
Related Documents
:
|
16584323 - Purdue university-banfield national companion animal surveillance program for emerging ... 11149973 - Osler's pathology. 22415613 - Ligand binding assays in the 21st century laboratory: recommendations for characterizat... |
Publication Detail:
|
Type: Journal Article Date: 2010-02-10 |
Journal Detail:
|
Title: Drug discovery today Volume: 15 ISSN: 1878-5832 ISO Abbreviation: Drug Discov. Today Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-04-05 Completed Date: 2010-06-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9604391 Medline TA: Drug Discov Today Country: England |
Other Details:
|
Languages: eng Pagination: 260-4 Citation Subset: IM |
Copyright Information:
|
2010 Elsevier Ltd. All rights reserved. |
Affiliation:
|
F. Hoffmann-La Roche, Grenzacherstrasse 124, PRCB, Building 92/8.88, CH-4070 Basel, Switzerland. cheryl.l.bishop@uk.pwc.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Academic Medical Centers
/
trends* Chemistry, Pharmaceutical / trends* Drug Discovery / trends* Drug Industry / trends* Molecular Biology / trends* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Stem cell therapies for ocular surface disease.
Next Document: Evaluation of different cytotoxic and cytostatic measures for the in vitro micronucleus test (MNVit)...