| Fusion of phospholipid vesicles induced by phospholipase D in the presence of calcium ion. | |
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MedLine Citation:
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PMID: 1417878 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fusion of phospholipid vesicles composed of various combination of phosphatidylcholine, phosphatidylethanolamine and phosphatidic acid was induced by Ca2+ in the presence or absence of phospholipase D from Streptomyces chromofuscus. For the vesicles composed of 20:50:30 molar ratio of phosphatidylcholine/phosphatidylethanolamine/phosphatidic acid, the initial fusion rate was much faster than the expected value when only the conversion of phosphatidylcholine and phosphatidylethanolamine into phosphatidic acid by phospholipase D is taken into account. These observations are discussed in terms of the involvement of outer monolayer of the vesicles and the enzyme activity itself in the fusion process. |
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Authors:
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J B Park; T H Lee; H Kim |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biochemistry international Volume: 27 ISSN: 0158-5231 ISO Abbreviation: Biochem. Int. Publication Date: 1992 Jul |
Date Detail:
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Created Date: 1992-11-20 Completed Date: 1992-11-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8100311 Medline TA: Biochem Int Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 417-22 Citation Subset: IM |
Affiliation:
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Department of Life Science, Korea Advanced Institute of Science and Technology, Yuseong-Gu, Taejon. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Calcium
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pharmacology* Drug Synergism Liposomes* Membrane Fusion / drug effects* Phosphatidic Acids / metabolism Phosphatidylcholines / metabolism Phosphatidylethanolamines / metabolism Phospholipase D / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Liposomes; 0/Phosphatidic Acids; 0/Phosphatidylcholines; 0/Phosphatidylethanolamines; 7440-70-2/Calcium; EC 3.1.4.4/Phospholipase D |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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