Document Detail


Fusion of erythrolysosomes in epithelial cells of the sheep placenta.
MedLine Citation:
PMID:  519719     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In trophoblastic epithelial cells of the sheep placenta the breakdown of erythrocytes within complex erythrolysosomes was studied at the ultrastructural level. It was found that the formation of complex erythrolysosomes containing from two to several erythrocytes as a result of fusion of erythrolysosomes within the epithelial cells was a common occurrence when the epithelial cells engulfed a large number of erythrocytes. The erythrocytes enclosed in complex erythrolysosomes appear to be either in the same or in different stages of hemolysis. In the process of breakdown of erythrocytes within complex erythrolysosomes five successive stages of hemolysis could be distinguished. Acid phosphatase activity was demonstrated in the complex erythrolysosomes and appeared to be located in the angular interspaces between the erythrocytes and the lysosomal membrane. The fragmentation of complex erythrolysosomes with formation of small hemoglobin-containing lysosomes also occurred. The fusion of erythrolysosomes with formation of complex erythrolysosomes can be considered as an additional mechanism in the process of erythrocyte breakdown in the epithelial cells of the sheep placenta.
Authors:
G Myagkaya; W T Daems
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell and tissue research     Volume:  203     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1979  
Date Detail:
Created Date:  1980-03-24     Completed Date:  1980-03-24     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  209-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acid Phosphatase / analysis
Animals
Epithelium / ultrastructure
Erythrocytes / ultrastructure
Female
Hemolysis*
Lysosomes / enzymology,  physiology,  ultrastructure*
Pregnancy
Sheep / anatomy & histology*
Trophoblasts / ultrastructure*
Chemical
Reg. No./Substance:
EC 3.1.3.2/Acid Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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