| Fusion of dynamic contrast-enhanced magnetic resonance mammography at 3.0T with X-ray mammograms: Pilot study evaluation using dedicated semi-automatic registration software. | |
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MedLine Citation:
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PMID: 21570793 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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RATIONALE AND OBJECTIVES: To evaluate the semi-automatic image registration accuracy of X-ray-mammography (XR-M) with high-resolution high-field (3.0T) MR-mammography (MR-M) in an initial pilot study. MATERIAL AND METHODS: MR-M was acquired on a high-field clinical scanner at 3.0T (T1-weighted 3D VIBE±Gd). XR-M was obtained with state-of-the-art full-field digital systems. Seven patients with clearly delineable mass lesions >10mm both in XR-M and MR-M were enrolled (exclusion criteria: previous breast surgery; surgical intervention between XR-M and MR-M). XR-M and MR-M were matched using a dedicated image-registration algorithm allowing semi-automatic non-linear deformation of MR-M based on finite-element modeling. To identify registration errors (RE) a virtual craniocaudal 2D mammogram was calculated by the software from MR-M (with and w/o Gadodiamide/Gd) and matched with corresponding XR-M. To quantify REs the geometric center of the lesions in the virtual vs. conventional mammogram were subtracted. The robustness of registration was quantified by registration of X-MRs to both MR-Ms with and w/o Gadodiamide. RESULTS: Image registration was performed successfully for all patients. Overall RE was 8.2mm (1min after Gd; confidence interval/CI: 2.0-14.4mm, standard deviation/SD: 6.7mm) vs. 8.9mm (no Gd; CI: 4.0-13.9mm, SD: 5.4mm). The mean difference between pre- vs. post-contrast was 0.7mm (SD: 1.9mm). CONCLUSION: Image registration of high-field 3.0T MR-mammography with X-ray-mammography is feasible. For this study applying a high-resolution protocol at 3.0T, the registration was robust and the overall registration error was sufficient for clinical application. |
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Authors:
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Matthias Dietzel; Torsten Hopp; Nicole Ruiter; Ramy Zoubi; Ingo B Runnebaum; Werner A Kaiser; Pascal A T Baltzer |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-12 |
Journal Detail:
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Title: European journal of radiology Volume: - ISSN: 1872-7727 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier Ireland Ltd. |
Affiliation:
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Institute of Diagnostic and Interventional Radiology, Friedrich-Schiller-University Jena, Erlanger Allee 101, D-07740 Jena, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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