Document Detail

Further insights into normal aortic valve function: role of a compliant aortic root on leaflet opening and valve orifice area.
MedLine Citation:
PMID:  14992884     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This study aims to find the fundamental differences in the mechanism of opening and closing of a normal aortic valve and a valve with a stiff root, using a dynamic finite element model. METHODS: A dynamic, finite element model with time varying pressure was used in this study. Shell elements with linear elastic properties for the leaflet and root were used. Two different cases were analyzed: (1) normal leaflets inside a compliant root, and (2) normal leaflets inside a stiff root. RESULTS: A compliant aortic root contributes substantially to the smooth and symmetrical leaflet opening with minimal gradients. In contrast, the leaflet opening inside a stiff root is delayed, asymmetric, and wrinkled. However, this wrinkling is not associated with increased leaflet stresses. In compliant roots, the effective valve orifice area can substantially increase because of increased root pressure and transvalvular gradients. In stiff roots this effect is strikingly absent. CONCLUSIONS: A compliant aortic root contributes substantially to smooth and symmetrical leaflet opening with minimal gradients. The compliance also contributes much to the ability of the normal aortic valve to increase its effective valve orifice in response to physiologic demands of exercise. This effect is strikingly absent in stiff roots.
Vangipuram Canchi Sripathi; Ramarathnam Krishna Kumar; Komarakshi R Balakrishnan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  77     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-03-02     Completed Date:  2004-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  844-51     Citation Subset:  AIM; IM    
Department of Mechanical Engineering, Indian Institute of Technology Madras, Chennai, India.
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MeSH Terms
Aortic Valve / anatomy & histology*,  physiology*
Computer Simulation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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