Document Detail

Further insights into coronary debulking: the EUROCARE trial of directional atherectomy and the PACT trial of pullback atherectomy.
MedLine Citation:
PMID:  11244515     Owner:  NLM     Status:  MEDLINE    
Although the principle of reducing plaque load in the coronary artery remains very appealing, clinical benefit from debulking devices has not been demonstrated unequivocally. Other approaches to prevent restenosis had been the application of various pharmacological agents. Unfortunately, the majority of clinical studies have not reproduced the promising results observed in the experimental laboratories. New frontiers in improving atherectomy devices and in optimizing concomitant medical treatment are currently being explored. We report on the EUROCARE trial investigating the possible benefit of carvedilol after coronary atherectomy, and the Pullback Atherectomy (PAC) pilot trial using a novel atherectomy device.
A Thury; G Van Langenhove; A J Wardeh; D P Foley; P W Serruys
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Review    
Journal Detail:
Title:  Seminars in interventional cardiology : SIIC     Volume:  5     ISSN:  1084-2764     ISO Abbreviation:  Semin Interv Cardiol     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-03-13     Completed Date:  2001-04-12     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  9606070     Medline TA:  Semin Interv Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  185-92     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Harcourt Publishers Ltd.
Department of Interventional Cardiology, Thoraxcenter, University Hospital Dijzigt, Rotterdam, The Netherlands
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use*
Antioxidants / therapeutic use*
Atherectomy, Coronary* / instrumentation
Carbazoles / therapeutic use*
Coronary Artery Disease / drug therapy,  therapy*
Equipment Design
Propanolamines / therapeutic use*
Randomized Controlled Trials as Topic
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Antioxidants; 0/Carbazoles; 0/Propanolamines; 0K47UL67F2/carvedilol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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