Document Detail


Further insights into coronary debulking: the EUROCARE trial of directional atherectomy and the PACT trial of pullback atherectomy.
MedLine Citation:
PMID:  11244515     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although the principle of reducing plaque load in the coronary artery remains very appealing, clinical benefit from debulking devices has not been demonstrated unequivocally. Other approaches to prevent restenosis had been the application of various pharmacological agents. Unfortunately, the majority of clinical studies have not reproduced the promising results observed in the experimental laboratories. New frontiers in improving atherectomy devices and in optimizing concomitant medical treatment are currently being explored. We report on the EUROCARE trial investigating the possible benefit of carvedilol after coronary atherectomy, and the Pullback Atherectomy (PAC) pilot trial using a novel atherectomy device.
Authors:
A Thury; G Van Langenhove; A J Wardeh; D P Foley; P W Serruys
Related Documents :
9761095 - Clinical and angiographic outcome after stent placement for chronic coronary occlusion.
16308495 - Elevated preprocedural high-sensitivity c-reactive protein levels are associated with n...
14563575 - A randomized trial of polytetrafluoroethylene-membrane-covered stents compared with con...
16020495 - Clinical restenosis after coronary stent implantation is associated with the heme oxyge...
24646835 - Dysmetropsia and cotard's syndrome due to migrainous infarction - or not?
9771175 - The peri-operative management of atrial fibrillation.
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Review    
Journal Detail:
Title:  Seminars in interventional cardiology : SIIC     Volume:  5     ISSN:  1084-2764     ISO Abbreviation:  Semin Interv Cardiol     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-03-13     Completed Date:  2001-04-12     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  9606070     Medline TA:  Semin Interv Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  185-92     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Harcourt Publishers Ltd.
Affiliation:
Department of Interventional Cardiology, Thoraxcenter, University Hospital Dijzigt, Rotterdam, The Netherlands
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / therapeutic use*
Antioxidants / therapeutic use*
Atherectomy, Coronary* / instrumentation
Carbazoles / therapeutic use*
Coronary Artery Disease / drug therapy,  therapy*
Equipment Design
Humans
Propanolamines / therapeutic use*
Randomized Controlled Trials as Topic
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Antioxidants; 0/Carbazoles; 0/Propanolamines; 0K47UL67F2/carvedilol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Morphological analysis of atherosclerotic plaque retrieved by coronary atherectomy.
Next Document:  Directional coronary atherectomy: optimal atherectomy trials and new combined strategies with corona...