| Further insights into coronary debulking: the EUROCARE trial of directional atherectomy and the PACT trial of pullback atherectomy. | |
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MedLine Citation:
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PMID: 11244515 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although the principle of reducing plaque load in the coronary artery remains very appealing, clinical benefit from debulking devices has not been demonstrated unequivocally. Other approaches to prevent restenosis had been the application of various pharmacological agents. Unfortunately, the majority of clinical studies have not reproduced the promising results observed in the experimental laboratories. New frontiers in improving atherectomy devices and in optimizing concomitant medical treatment are currently being explored. We report on the EUROCARE trial investigating the possible benefit of carvedilol after coronary atherectomy, and the Pullback Atherectomy (PAC) pilot trial using a novel atherectomy device. |
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Authors:
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A Thury; G Van Langenhove; A J Wardeh; D P Foley; P W Serruys |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Review |
Journal Detail:
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Title: Seminars in interventional cardiology : SIIC Volume: 5 ISSN: 1084-2764 ISO Abbreviation: Semin Interv Cardiol Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2001-03-13 Completed Date: 2001-04-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9606070 Medline TA: Semin Interv Cardiol Country: England |
Other Details:
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Languages: eng Pagination: 185-92 Citation Subset: IM |
Copyright Information:
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Copyright 2000 Harcourt Publishers Ltd. |
Affiliation:
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Department of Interventional Cardiology, Thoraxcenter, University Hospital Dijzigt, Rotterdam, The Netherlands |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use* Antioxidants / therapeutic use* Atherectomy, Coronary* / instrumentation Carbazoles / therapeutic use* Coronary Artery Disease / drug therapy, therapy* Equipment Design Humans Propanolamines / therapeutic use* Randomized Controlled Trials as Topic |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Antioxidants; 0/Carbazoles; 0/Propanolamines; 72956-09-3/carvedilol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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