Document Detail

Further improvement in IVF outcome may need more than consistency in ovarian stimulation.
MedLine Citation:
PMID:  16895624     Owner:  NLM     Status:  MEDLINE    
It is agreed that reliability of hormonal products, starting with recombinant technology, has improved uniformity of ovarian response to a specified dosage, and that this has resulted in better pregnancy rates. Nevertheless, IVF cycle cancellation rate has not experienced a substantial decline in the last 5-10 years. We feel that further improvement will be more likely to be achieved once we gain better understanding of factors intrinsic to oocyte biology, such as oocyte ageing and oocyte depletion.
Jose P Balmaceda; Juan-Enrique Schwarze
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  13     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-09     Completed Date:  2006-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  156-7     Citation Subset:  IM    
Reproductive Medicine Unit, Clinica Las Condes, Lo Fontecilla 441, Santiago, Chile.
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MeSH Terms
Fertilization in Vitro / standards*
Follicle Stimulating Hormone / therapeutic use*
Follicle Stimulating Hormone, Human / therapeutic use
Glycoprotein Hormones, alpha Subunit / therapeutic use
Infertility, Female / drug therapy
Ovulation Induction / standards*
Pregnancy Rate
Reg. No./Substance:
0/Follicle Stimulating Hormone, Human; 0/Glycoprotein Hormones, alpha Subunit; 9002-68-0/Follicle Stimulating Hormone
Comment On:
Reprod Biomed Online. 2006 Jun;12(6):663-8   [PMID:  16792840 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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