Document Detail


Further developments in the neurobiology of food and addiction: update on the state of the science.
MedLine Citation:
PMID:  22305533     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Over the past three decades, obesity has become a major public health crisis in the United States. The prevalence of obesity in the United States and in other parts of the world has led to a new word, "globesity," being used to describe the problem. As a result of this increased emphasis on understanding the causes and consequences of obesity, novel theories have stimulated new research aimed to prevent, intervene in and ameliorate the effects and decrease the incidence and medical consequences of globesity. One theory that has gained popularity in recent years, is based on the idea that an excessive intake of highly palatable foods shares similarities with the effects on brain and behavior that are seen with some drugs of abuse. Although this theory is not new, empirically-based translational research has only recently provided strong support for this hypothesis. In the present article, we review the present state of the science in this area and describe some newer clinical and preclinical works that shed light on innovative and interesting overlaps between excessivly palatable food intake and drug use.
Authors:
Nicole M Avena; Jessica A Gold; Cindy Kroll; Mark S Gold
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2012-02-03
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  28     ISSN:  1873-1244     ISO Abbreviation:  Nutrition     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-14     Completed Date:  2012-08-01     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  341-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Psychiatry, University of Florida, College of Medicine, Gainesville, Florida, USA. navena@ufl.edu
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MeSH Terms
Descriptor/Qualifier:
Behavior, Addictive*
Brain*
Diet / psychology*
Energy Intake*
Food Preferences / psychology*
Humans
Neurobiology
Obesity / epidemiology,  psychology*
Substance-Related Disorders / psychology*
United States
Grant Support
ID/Acronym/Agency:
DA-030123-01/DA/NIDA NIH HHS; K01 DA031230/DA/NIDA NIH HHS; K01 DA031230-01/DA/NIDA NIH HHS; UL1 TR000064/TR/NCATS NIH HHS
Comments/Corrections

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