| Furosemide pharmacokinetics and pharmacodynamics in health and disease--an update. | |
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MedLine Citation:
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PMID: 2654356 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The literature on furosemide pharmacokinetics and pharmacodynamics is critically reviewed, concentrating on those papers published subsequent to the 1979 reviews of this topic. Intravenous and oral data are presented for healthy volunteers and for patients with various disease states. It is the latter populations about which the majority of the studies have been published since 1979. Inter- and intraindividual variations in bioavailability are discussed, as are data on the metabolism of furosemide to its glucuronide conjugate. Published studies examining the relationship between furosemide pharmacodynamics and pharmacokinetics are also evaluated. The literature is reviewed through June 1988. |
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Authors:
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M Hammarlund-Udenaes; L Z Benet |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Journal of pharmacokinetics and biopharmaceutics Volume: 17 ISSN: 0090-466X ISO Abbreviation: J Pharmacokinet Biopharm Publication Date: 1989 Feb |
Date Detail:
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Created Date: 1989-06-22 Completed Date: 1989-06-22 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0357115 Medline TA: J Pharmacokinet Biopharm Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1-46 Citation Subset: IM |
Affiliation:
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Department of Pharmacy, School of Pharmacy, University of California, San Francisco 94143-0446. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Disease
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metabolism Furosemide / pharmacokinetics*, pharmacology Health Humans |
| Grant Support | |
ID/Acronym/Agency:
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GM26691/GM/NIGMS NIH HHS; GM36633/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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54-31-9/Furosemide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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