Document Detail

Fungi: toxic killers or unavoidable nuisances?
MedLine Citation:
PMID:  11770685     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: This discussion is focused on the many roles of fungi in human health, and also to put the mycotoxin literature into perspective. DATA SOURCES: Data are derived from the literature referenced in PubMed from the National Library of Medicine, earlier references in the authors' reprint collection, and ongoing research. Studies for review were either selected from the peer-reviewed literature or from standard texts that are well recognized in the field. RESULTS: The review yielded many studies of the role of fungi in allergic disease, but none that systematically documented such a role for mycotoxins or fungal volatiles. Many case studies were found, but none of these unequivocally document a cause/effect relationship between mycotoxin exposure by inhalation and human disease in residential, school, or office settings. CONCLUSIONS: The review led to the conclusion that that the primary result from fungal exposure is allergic disease, and that the evidence for inhalation disease resulting from mycotoxin exposure in residential and office settings is extremely weak.
H A Burge
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology     Volume:  87     ISSN:  1081-1206     ISO Abbreviation:  Ann. Allergy Asthma Immunol.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-27     Completed Date:  2002-01-16     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9503580     Medline TA:  Ann Allergy Asthma Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  52-6     Citation Subset:  IM    
Harvard School of Public Health, Boston, Massachusetts 02215, USA.
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MeSH Terms
Administration, Inhalation
Allergens / adverse effects*,  immunology
Fungi / immunology*,  metabolism*
Hypersensitivity / etiology*
Mycotoxins / adverse effects*,  immunology
Spores, Fungal / immunology
Reg. No./Substance:
0/Allergens; 0/Mycotoxins
Comment In:
Ann Allergy Asthma Immunol. 2003 Aug;91(2):212-3; author reply 213-5   [PMID:  12952119 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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