| Fungal urinary tract infections in patients at risk. | |
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MedLine Citation:
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PMID: 10394985 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fungal urinary tract infection (UTI) represents a high-risk event in severely ill patients. Its increasing incidence in recent years is associated with extensive and prolonged use of broad-spectrum antimicrobial agents, corticosteroids, immunosuppressive and cytotoxic drugs. Other important risk factors comprise higher age, diabetes mellitus, chronic renal failure, hemodialysis, renal transplantation, structural or functional abnormalities of urinary tract with indwelling urinary catheter or nephrostomy. Fifty hospitalized symptomatic patients with funguria of > 10(5) CFU/ml and leucocyturia were analysed for etiology, risk factors and outcome. Candida albicans was isolated in 36 patients, non-albicans Candida species (Candida tropicalis, Candida krusei) and non-Candida yeasts (Blastoschizomyces capitatus) in 14 patients, respectively. All patients were treated with systemic antifungals. In total, 42 patients of 50 (84%) were cured (32/36 with C. albicans and 10/14 with non-C. albicans associated funguria). Systemic antifungal therapy should be considered in high-risk patients with fungal UTI. |
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Authors:
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S Krcmery; M Dubrava; V Krcmery |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of antimicrobial agents Volume: 11 ISSN: 0924-8579 ISO Abbreviation: Int. J. Antimicrob. Agents Publication Date: 1999 May |
Date Detail:
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Created Date: 1999-08-24 Completed Date: 1999-08-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9111860 Medline TA: Int J Antimicrob Agents Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 289-91 Citation Subset: IM |
Affiliation:
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Department of Geriatric Medicine, Comenius University School of Medicine, Bratislava, Slovak Republic. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antifungal Agents
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therapeutic use* Candidiasis / drug therapy* Female Humans Male Middle Aged Risk Factors Urinary Tract Infections / drug therapy*, epidemiology, microbiology |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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