Document Detail

Fungal urinary tract infections in patients at risk.
MedLine Citation:
PMID:  10394985     Owner:  NLM     Status:  MEDLINE    
Fungal urinary tract infection (UTI) represents a high-risk event in severely ill patients. Its increasing incidence in recent years is associated with extensive and prolonged use of broad-spectrum antimicrobial agents, corticosteroids, immunosuppressive and cytotoxic drugs. Other important risk factors comprise higher age, diabetes mellitus, chronic renal failure, hemodialysis, renal transplantation, structural or functional abnormalities of urinary tract with indwelling urinary catheter or nephrostomy. Fifty hospitalized symptomatic patients with funguria of > 10(5) CFU/ml and leucocyturia were analysed for etiology, risk factors and outcome. Candida albicans was isolated in 36 patients, non-albicans Candida species (Candida tropicalis, Candida krusei) and non-Candida yeasts (Blastoschizomyces capitatus) in 14 patients, respectively. All patients were treated with systemic antifungals. In total, 42 patients of 50 (84%) were cured (32/36 with C. albicans and 10/14 with non-C. albicans associated funguria). Systemic antifungal therapy should be considered in high-risk patients with fungal UTI.
S Krcmery; M Dubrava; V Krcmery
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of antimicrobial agents     Volume:  11     ISSN:  0924-8579     ISO Abbreviation:  Int. J. Antimicrob. Agents     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-08-24     Completed Date:  1999-08-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9111860     Medline TA:  Int J Antimicrob Agents     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  289-91     Citation Subset:  IM    
Department of Geriatric Medicine, Comenius University School of Medicine, Bratislava, Slovak Republic.
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MeSH Terms
Antifungal Agents / therapeutic use*
Candidiasis / drug therapy*
Middle Aged
Risk Factors
Urinary Tract Infections / drug therapy*,  epidemiology,  microbiology
Reg. No./Substance:
0/Antifungal Agents

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