Document Detail


Fungal postoperative spondylodiscitis due to Scedosporium prolificans.
MedLine Citation:
PMID:  19447683     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND CONTEXT: Postoperative fungal spondylodiscitis is a rare infectious disease. PURPOSE: We report the first case of postoperative spondylodiscitis because of Scedosporium prolificans and review postoperative vertebral infection caused by fungi. STUDY DESIGN/SETTING: Medline search. METHODS: Case report and literature review. RESULTS: On reviewing the cases of postoperative fungal spondylodiscitis reported so far in the literature, we found eight were caused by mold, and five by yeast. Clinically, the disease presents similar to postoperative vertebral osteomyelitis caused by bacteria, and a high clinical index of suspicion may be required to perform appropriate cultures to establish a diagnosis. Our review revealed a significant number of cases that were cured after surgical debridement and/or antifungal therapy. CONCLUSIONS: On the basis of this limited assessment, it appears that the clinical course and prognosis of postoperative fungal spondylodiscitis is similar to that reported for postoperative pyogenic spondylodiscitis.
Authors:
Carolina Garcia-Vidal; Carmen Cabellos; Josefina Ayats; Frederic Font; Enrique Ferran; Pedro Fernandez-Viladrich
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-05-17
Journal Detail:
Title:  The spine journal : official journal of the North American Spine Society     Volume:  9     ISSN:  1878-1632     ISO Abbreviation:  -     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-24     Completed Date:  2009-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130732     Medline TA:  Spine J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e1-7     Citation Subset:  IM    
Affiliation:
Infectious Disease Service, IDIBELL-Hospital Universitary de Bellvitge, University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain. carolgv75@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / therapeutic use
Antifungal Agents / therapeutic use
Arthrodesis
Debridement
Discitis / microbiology*,  pathology,  surgery
Female
Humans
Intervertebral Disk Displacement / surgery
Magnetic Resonance Imaging
Middle Aged
Mycoses / etiology,  microbiology*,  pathology
Orthopedic Procedures / adverse effects
Postoperative Complications / microbiology*
Pyrimidines / therapeutic use
Scedosporium*
Triazoles / therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Antifungal Agents; 0/Pyrimidines; 0/Triazoles; 0/voriconazole

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