Document Detail

Fungal granuloma of the brain caused by Cladosporium bantianum--a case report and review of literature.
MedLine Citation:
PMID:  15607219     Owner:  NLM     Status:  MEDLINE    
Involvement of the brain by neurotropic, dematiaceous fungi namely Cladosporium bantianum is extremely rare. The disease is very resistant to treatment and prone for frequent relapses despite treatment with amphotericin B and flucytosine, the drugs of choice for the infection. Surgery is often required for resection of the fungal granuloma. Isolation of the fungus from the tissue specimens and its culture, showing dark colored fungal colonies clinches the diagnosis. Animal inoculation studies can provide insights to the portal of entry of the organism. We hereby report a case of fungal granuloma of the brain due to C. bantianum, which responded favorably to intensive antifungal treatment alone, with relevant review of literature.
Sumit Singh; Prabhjeet Singh; Chitra Sarkar; Vinay Goel; Trilochan Srivastava; M C Sharma; Madhuri Behari
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2004-11-19
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  228     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-20     Completed Date:  2005-04-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  109-12     Citation Subset:  IM    
Department of Neurology, 702, Neurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
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MeSH Terms
Amphotericin B / therapeutic use
Antifungal Agents / therapeutic use
Brain Diseases / complications,  drug therapy,  microbiology*
Fluconazole / therapeutic use
Granuloma / complications,  drug therapy,  microbiology*
Headache / drug therapy,  etiology
Magnetic Resonance Imaging / methods
Review Literature as Topic
Staining and Labeling / methods
Reg. No./Substance:
0/Antifungal Agents; 1397-89-3/Amphotericin B; 86386-73-4/Fluconazole

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