Document Detail


The Funen Adenoma Follow-Up Study. Characteristics of patients and initial adenomas in relation to severe dysplasia.
MedLine Citation:
PMID:  8446849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Between 1978 and 1992 a total of 1689 colorectal adenomas were removed in 1042 patients with no history of previous colorectal neoplasms. One hundred and eighteen patients had at least one adenoma with severe dysplasia. A 'clean colon' was ensured by total colonoscopy in 97% of the patients. A multiple logistic model was used to assess the independent risk factors associated with severe dysplasia. The size of largest adenoma and the extent of villous component were identified as independent patient risk factors associated with high risk of severe dysplasia. The results indicated that the risk of severe dysplasia is high in patients with large and/or villous adenomas and the risk is even higher when the adenomas are found in the sigmoid colon or rectum.
Authors:
O D Jørgensen; O Kronborg; C Fenger
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of gastroenterology     Volume:  28     ISSN:  0036-5521     ISO Abbreviation:  Scand. J. Gastroenterol.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-04-07     Completed Date:  1993-04-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060105     Medline TA:  Scand J Gastroenterol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  239-43     Citation Subset:  IM    
Affiliation:
Dept. of Surgical Gastroenterology, Odense University Hospital, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Adenoma / pathology*
Adult
Aged
Colorectal Neoplasms / pathology*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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