| Fundus autofluorescence and multiple evanescent white dot syndrome. | |
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MedLine Citation:
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PMID: 18936716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To describe fundus autofluorescence (FAF) in a series of patients with multiple evanescent white dot syndrome. METHODS: Three eyes of three patients with multiple evanescent white dot syndrome were evaluated with indocyanine green angiography and FAF imaging to evaluate the correspondence between FAF and ICG patterns and the nature of the focal hypocyanescent spots evident with ICG. RESULTS: In the acute phase, all three eyes showed increased autofluorescence area corresponding precisely to the site of the focal hypocyanescent spots seen on ICG but less numerous. After 2 months, mean best-corrected visual acuity improved from 20/38 to 20/20 and FAF and indocyanine green angiography returned to normal pattern. DISCUSSION: FAF is an useful noninvasive diagnostic adjunct to identify multiple evanescent white dot syndrome, suggesting the inflammatory nature of the disease, probably due to perturbation of the photoreceptor-retinal pigment epithelium complex affecting the function of these cells. |
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Authors:
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Claudio Furino; Francesco Boscia; Nicola Cardascia; Giovanni Alessio; Carlo Sborgia |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Retina (Philadelphia, Pa.) Volume: 29 ISSN: 1539-2864 ISO Abbreviation: Retina (Philadelphia, Pa.) Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2009-01-09 Completed Date: 2009-03-06 Revised Date: 2009-11-30 |
Medline Journal Info:
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Nlm Unique ID: 8309919 Medline TA: Retina Country: United States |
Other Details:
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Languages: eng Pagination: 60-3 Citation Subset: IM |
Affiliation:
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Dipartimento di Oftalmologia ed Otorinolaringoiatria, Università di Bari, Bari, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Coloring Agents / diagnostic use Female Fluorescein Angiography* Fluorescence Fundus Oculi Humans Indocyanine Green / diagnostic use Ophthalmoscopy Retina / pathology* Retinal Diseases / diagnosis* Retinal Pigment Epithelium / pathology* Syndrome Visual Acuity Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Coloring Agents; 3599-32-4/Indocyanine Green |
| Comments/Corrections | |
Comment In:
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Retina. 2009 Oct;29(9):1377-8; author reply 1378-9
[PMID:
19934830
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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