| Fundic gland polyps (Elster's cysts) of the gastric mucosa. A marker for colorectal epithelial neoplasia? | |
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MedLine Citation:
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PMID: 12530575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The results of several retrospective studies allow us to conclude that the detection of fundic gland polyps (Elster's cysts) is associated with an increased incidence of colorectal tumors. In this survey, we present the results of a prospective study investigating such a possible relationship. A total of 144 patients were investigated, of whom 80 had fundic gland polyps of the gastric corpus mucosa. Sixty-four of these patients underwent a colonoscopy, whereas the other 64 patients belonged to a sex- and age-matched control group with no fundic gland polyps. In the group with known fundic gland polyps, colorectal neoplasias were found in 29 (45.3%) patients. Eight of these patients had (12.5%) adenocarcinomas, 3 (4.7%) had high-grade intraepithelial neoplasia, and 18 (28.1%) had tubular adenomas. In one patient, a synchronous carcinoma of the rectum and the colon was detected. In comparison, 6 patients of the control group (9.3%) developed tubular adenomas and 9 (14.1%) had hyperplastic polyps of the colonic and rectal mucosa. Our results suggest that it is necessary to conduct a careful diagnostic work-up of the colon in patients with gastric fundic gland polyps. |
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Authors:
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A Jung; M Vieth; O Maier; M Stolte |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pathology, research and practice Volume: 198 ISSN: 0344-0338 ISO Abbreviation: Pathol. Res. Pract. Publication Date: 2002 |
Date Detail:
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Created Date: 2003-01-17 Completed Date: 2003-06-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7806109 Medline TA: Pathol Res Pract Country: Germany |
Other Details:
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Languages: eng Pagination: 731-4 Citation Subset: IM |
Affiliation:
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Praxis für Gastroenterologie, Augsburg, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Colonoscopy Colorectal Neoplasms / complications* Female Gastric Fundus / pathology* Gastric Mucosa / pathology Humans Male Middle Aged Polyps / complications*, pathology Prospective Studies Tumor Markers, Biological / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Tumor Markers, Biological |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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