| Fundamentals of quantitative dynamic contrast-enhanced MR imaging. | |
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MedLine Citation:
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PMID: 19406359 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Quantitative analysis of dynamic contrast-enhanced MR imaging (DCE-MR imaging) has the power to provide information regarding physiologic characteristics of the microvasculature and is, therefore, of great potential value to the practice of oncology. In particular, these techniques could have a significant impact on the development of novel anticancer therapies as a promising biomarker of drug activity. Standardization of DCE-MR imaging acquisition and analysis to provide more reproducible measures of tumor vessel physiology is of crucial importance to realize this potential. The purpose of this article is to review the pathophysiologic basis and technical aspects of DCE-MR imaging techniques. |
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Authors:
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Michael J Paldino; Daniel P Barboriak |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Magnetic resonance imaging clinics of North America Volume: 17 ISSN: 1557-9786 ISO Abbreviation: Magn Reson Imaging Clin N Am Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-01 Completed Date: 2009-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9422762 Medline TA: Magn Reson Imaging Clin N Am Country: United States |
Other Details:
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Languages: eng Pagination: 277-89 Citation Subset: IM |
Affiliation:
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Division of Neuroradiology, Department of Radiology, Duke University Medical Center, Box 3808, Erwin Road, Durham, NC 27710, USA. paldi001@mc.duke.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Contrast Media
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pharmacokinetics* Diagnosis, Differential Gadolinium / diagnostic use, pharmacokinetics* Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods Magnetic Resonance Imaging / methods* Mathematics Neoplasms / blood supply, diagnosis*, pathology Neovascularization, Pathologic / diagnosis*, pathology Tumor Markers, Biological / analysis |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Tumor Markers, Biological; 7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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