| Functionalized pyrolytic highly oriented graphite polymer film for surface-assisted laser desorption/ionization mass spectrometry in environmental analysis. | |
| | |
MedLine Citation:
|
PMID: 19757448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The pyrolytic highly oriented graphite polymer film (PGS) was first employed to analyze low-mass analytes in environmental analysis by surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS). PGS is a synthetic uniform and highly oriented graphite polymer film with high thermal anisotropic conductivity. We have found that negative ion mode SALDI-MS using oxidized PGS (PGS-SALDI-MS) can be used to detect [M-H]- ions from perfluorooctanoic acid (PFOA) and other perfluoroalkylcarboxylic acids when the PGS surface is modified with the cationic polymer polyethyleneimine (PEI). The signal intensity of PFOA when employing the PEI modification showed a ten-fold increase over that obtained from desorption/ionization on porous silicon (DIOS). PFOA was quantified using PGS-SALDI-MS and the calibration curve showed a wide linear dynamic range of response (20-1000 ppb). The combination of atmospheric pressure ionization and PGS (AP-PGS-SALDI) showed greater signal intensity than vacuum PGS-SALDI for deprotonated PFOA. Several other environmentally important chemicals, including perfluoroalkylsulfonic acid, pentachlorophenol, bisphenol A, 4-hydroxy-2-chlorobiphenyl, and benzo[a]pyrene, were also successfully used to evaluate PGS-SALDI-MS. In addition, we found that nonafluoro-1-butanesulfonic acid was able to produce protonated peptides in positive ion PGS-SALDI-MS, but that perfluoropentanoic acid and trifluoroacetic acid were not. It is suggested that perfluoroalkylsulfonic acids are better protonating agents than perfluoroalkylcarboxylic acids in SALDI-MS. |
| | |
Authors:
|
Hideya Kawasaki; Naoyuki Takahashi; Hiroki Fujimori; Kouji Okumura; Takehiro Watanabe; Chisato Matsumura; Syusuke Takemine; Takeshi Nakano; Ryuichi Arakawa |
Related Documents
:
|
15543978 - Novel urea-linked cinchona-calixarene hybrid-type receptors for efficient chromatograph... 1443568 - Two-dimensional mapping of n-glycosidically linked asialo-oligosaccharides from glycopr... 833228 - Quantitation of patulin pathway metabolites using gas-liquid chromatography. 8491808 - Quantification of physiological amino acids by gradient ion-exchange high-performance l... 15285328 - Transdermal delivery of ketorolac tromethamine: effects of vehicles and penetration enh... 17496338 - Influence of inhibitory compounds and minor sugars on xylitol production by debaryomyce... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Rapid communications in mass spectrometry : RCM Volume: 23 ISSN: 1097-0231 ISO Abbreviation: Rapid Commun. Mass Spectrom. Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-09-23 Completed Date: 2009-11-25 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8802365 Medline TA: Rapid Commun Mass Spectrom Country: England |
Other Details:
|
Languages: eng Pagination: 3323-32 Citation Subset: IM |
Copyright Information:
|
Copyright 2009 John Wiley & Sons, Ltd. |
Affiliation:
|
Department of Applied Chemistry, Kansai University, Suita, Osaka 564-8680, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Environmental Pollutants
/
chemistry* Fluorocarbons / chemistry Graphite / chemistry* Octanoic Acids / chemistry Polymers / chemistry* Spectrometry, Mass, Electrospray Ionization / instrumentation*, methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / instrumentation*, methods |
| Chemical | |
Reg. No./Substance:
|
0/Environmental Pollutants; 0/Fluorocarbons; 0/Octanoic Acids; 0/Polymers; 335-67-1/perfluorooctanoic acid; 7782-42-5/Graphite |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Advantages of compound-specific stable isotope measurements over bulk measurements in studies on pla...
Next Document: Derivatization aids in the determination of end groups in poly(alkylene glycol)s by matrix-assisted ...