| Functionalized carbon nanotubes for potential medicinal applications. | |
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MedLine Citation:
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PMID: 20451656 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Functionalized carbon nanotubes display unique properties that enable a variety of medicinal applications, including the diagnosis and treatment of cancer, infectious diseases and central nervous system disorders, and applications in tissue engineering. These potential applications are particularly encouraged by their ability to penetrate biological membranes and relatively low toxicity. High aspect ratio, unique optical property and the likeness as small molecule make carbon nanotubes an unusual allotrope of element carbon. After functionalization, carbon nanotubes display potentials for a variety of medicinal applications, including the diagnosis and treatment of cancer, infectious diseases and central nervous system disorders, and applications in tissue engineering. These potential applications are particularly encouraged by their ability to penetrate biological membranes and relatively low toxicity. |
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Authors:
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Yi Zhang; Yuhong Bai; Bing Yan |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2010-05-06 |
Journal Detail:
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Title: Drug discovery today Volume: 15 ISSN: 1878-5832 ISO Abbreviation: Drug Discov. Today Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-08-05 Completed Date: 2010-11-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9604391 Medline TA: Drug Discov Today Country: England |
Other Details:
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Languages: eng Pagination: 428-35 Citation Subset: IM |
Copyright Information:
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(c) 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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School of Pharmaceutical Sciences, Shandong University, Jinan, 250100, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Central Nervous System Diseases / diagnosis, drug therapy Communicable Diseases / diagnosis, drug therapy Drug Carriers / adverse effects, chemistry* Drug Delivery Systems* Humans Nanotubes, Carbon / adverse effects, chemistry* Neoplasms / diagnosis, drug therapy Tissue Engineering / methods |
| Grant Support | |
ID/Acronym/Agency:
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P30CA021765/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Drug Carriers; 0/Nanotubes, Carbon |
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