Document Detail

Functional tricuspid regurgitation following replacement of the mitral valve.
MedLine Citation:
PMID:  1743791     Owner:  NLM     Status:  MEDLINE    
In this series, the effect of replacement of the mitral valve was examined in 86/900 (9.6%) patients who had developed moderate functional tricuspid regurgitation, secondary to rheumatic mitral valvar disease. These patients were subdivided according to the severity of pulmonary hypertension and impairment of right ventricular function. Forty-six patients presented with severe pulmonary hypertension and 40 patients had moderate pulmonary hypertension (mean main pulmonary arterial pressure: 78 +/- 14 mmHg vs 41 +/- 6 mmHg; P less than 0.05). The latter had more advanced disease, greater impairment of right ventricular function and dilatation of the right heart chambers. Functional tricuspid regurgitation regressed in 38/42 survivors with severe pulmonary hypertension and persisted or progressed significantly in 22/34 survivors with impaired right ventricular function despite successful replacement of the mitral valve. The latter underwent replacement of the tricuspid valve (n = 16) or tricuspid annuloplasty (n = 6), at a mean interval of 44 +/- 4.4 months after replacement of the mitral valve, which resulted in 8/22 (23.5%) early deaths. Functional tricuspid regurgitation is more likely to persist in patients with advanced right ventricular failure. Tricuspid valvar competence should be restored in these patients at initial replacement of the mitral valve.
T K Kaul; D R Ramsdale; J L Mercer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  33     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-01-13     Completed Date:  1992-01-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  305-13     Citation Subset:  IM    
Regional Adult Cardiothoracic Surgical Centre, Broadgreen Hospital, Liverpool, U.K.
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MeSH Terms
Follow-Up Studies
Heart Valve Prosthesis / adverse effects*
Hypertension, Pulmonary / etiology*,  mortality,  physiopathology
Middle Aged
Mitral Valve Stenosis / surgery*
Postoperative Complications / etiology*,  mortality,  physiopathology
Retrospective Studies
Risk Factors
Severity of Illness Index
Survival Rate
Tricuspid Valve Insufficiency / etiology*,  mortality,  physiopathology
Ventricular Function

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