Document Detail


Functional similarity between electrograms recorded from an implantable cardioverter defibrillator emulator and the surface electrocardiogram.
MedLine Citation:
PMID:  11227966     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clinical use of stored electrogram (EGM) configurations currently used in ICDs is limited. The hypothesis that EGMs recorded from electrodes on the ICD surface may improve diagnostic capabilities of the device was tested in the present study. The Buttons on Active Can Emulator (BACE), an ICD-sized device containing four button electrodes, was temporarily placed into a subcutaneous or submuscular left pectoral pocket in 16 patients during ICD implantation. Simultaneous recordings were obtained from the ECG lead II, bipolar EGMs using BACE electrodes, and a bipolar atrial EGM during sinus rhythm (SR), ventricular pacing (VP) at cycle lengths of 500 and 400 ms, and VT. Visible P waves were present in all patients during SR (n = 15), in 5 (33%) of 15 patients during VP, and none of the patients during VT (n = 4) using BACE EGMs and lead II. P and QRS amplitudes and the P:QRS ratio during SR in BACE EGMs were significantly lower than those in lead II. BACE EGMs showed prominent changes in QRS morphology and duration during VP and VT compared to SR, and the magnitude of QRS prolongation during VP was similar to that in lead II. Measurements of PR, QRS, and QT duration during SR showed good agreement between BACE EGMs and lead II. In conclusion, EGMs recorded from electrodes embedded on the ICD housing may potentially improve visual discrimination between supraventricular and ventricular arrhythmias. They also may be useful as a surrogate of the ECG for analysis and monitoring of different components of P-QRS-T complex.
Authors:
A Mazur; L Wang; M E Anderson; R Yee; H Theres; A Pearson; W Olson; M Wathen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  24     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-02-28     Completed Date:  2001-05-31     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-40     Citation Subset:  IM    
Affiliation:
Vanderbilt University Medical Center, Nashville, Tennessee 37232-6300, USA.
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MeSH Terms
Descriptor/Qualifier:
Defibrillators, Implantable*
Electrocardiography* / methods
Equipment Design
Feasibility Studies
Humans
Signal Processing, Computer-Assisted
Tachycardia, Ventricular / therapy
Grant Support
ID/Acronym/Agency:
HL03109/HL/NHLBI NIH HHS; HL03727/HL/NHLBI NIH HHS; HL62494/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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