| Functional significance of the decreased attenuation sign on expiratory CT in pulmonary sarcoidosis : report of four cases. | |
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MedLine Citation:
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PMID: 11296199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe four patients with proven sarcoidosis and minor pulmonary involvement according to high-resolution CT (HRCT) findings in whom the recently described sign of decreased attenuation on expiratory HRCT scan appeared associated with the reduction of the single-breath diffusing capacity of the lung for carbon monoxide (DLCO) and the DLCO adjusted for alveolar volume. These alterations were, in part, reversible under steroid treatment. Major indexes of airway obstruction (FEV(1)/vital capacity ratio and FEV(1)) were normal, while the maximum expiratory flow at 25% above the residual volume of FVC was reduced. These observations suggest that an expiratory HRCT mosaic pattern and diffusion impairment may be early findings in pulmonary sarcoidosis and may be useful for its detection and follow-up. |
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Authors:
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P Fazzi; P Sbragia; S Solfanelli; S Troilo; C Giuntini |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Chest Volume: 119 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 2001 Apr |
Date Detail:
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Created Date: 2001-04-11 Completed Date: 2001-05-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
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Languages: eng Pagination: 1270-4 Citation Subset: AIM; IM |
Affiliation:
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Cardiac and Thoracic Department, Respiratory Pathophysiology Section, University of Pisa, Italy. c.guintini@med.unipi.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carbon Dioxide / physiology Female Humans Lung / radiography* Middle Aged Pulmonary Diffusing Capacity Respiration Respiratory Mechanics Sarcoidosis, Pulmonary / physiopathology, radiography* Tomography, X-Ray Computed* |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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