| Functional residual capacity and compliance of the respiratory system after surfactant treatment in premature infants with severe respiratory distress syndrome. | |
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MedLine Citation:
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PMID: 12200607 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONCLUSION: the changes in lung function following surfactant treatment can only be explained by initial stabilisation of already aerated alveoli followed by recruitment of new gas exchange units as mechanisms involved in mediating the effect of surfactant on gas exchange. However, since no significant correlation between changes in functional residual capacity and improvement in arterial-to-alveolar oxygen tension ratio was seen, other effects of surfactant must be considered. These include local and/or systemic changes in haemodynamics. |
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Authors:
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Jürgen Dinger; Andreas Töpfer; Peter Schaller; Roland Schwarze |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article Date: 2002-07-12 |
Journal Detail:
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Title: European journal of pediatrics Volume: 161 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-08-29 Completed Date: 2003-03-04 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: Germany |
Other Details:
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Languages: eng Pagination: 485-90 Citation Subset: IM |
Affiliation:
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Klinik für Kinderheilkunde, Medizinische Fakultät, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany. Dinger@ukd80.med.tu-dresden.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Functional Residual Capacity* / drug effects Hemodynamics Humans Infant, Newborn Infant, Premature* Lung / drug effects*, physiology Lung Compliance / drug effects Male Pulmonary Gas Exchange / drug effects Pulmonary Surfactants / administration & dosage, therapeutic use* Respiratory Distress Syndrome, Newborn / drug therapy*, physiopathology Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Pulmonary Surfactants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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