| Functional neuroimaging in the assessment of CNS neoplasms. | |
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MedLine Citation:
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PMID: 9370545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Assessment of CNS neoplasms has focused traditionally on morphological analysis. Recent developments in MR sequence design now enable functional assessments. T1-weighted, as well as T2(*)-weighted, dynamic, gadolinium-enhanced, imaging can be used for assessment of vascularisation, permeability, and microcirculation of CNS neoplasms. Characterisation of cerebrovascular blood flow is possible using dynamic MR angiography, while neurofunctional imaging enables visualisation of local alterations in neuronal activity in stimulated cortical areas. Diffusion-weighted imaging can be used for improved delineation of neoplasms, while chemical shift imaging allows metabolic mapping of lesions and surrounding tissues. Implementation of these techniques can improve characterisation, information for therapy, planning and prognosis in clinical imaging of CNS neoplasms. |
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Authors:
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M V Knopp; M Essig; H Hawighorst; F Wenz; G Brix; L R Schad; P Bachert; G van Kaick |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: European radiology Volume: 7 Suppl 5 ISSN: 0938-7994 ISO Abbreviation: Eur Radiol Publication Date: 1997 |
Date Detail:
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Created Date: 1998-01-28 Completed Date: 1998-01-28 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 209-15 Citation Subset: IM |
Affiliation:
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Department of Radiological Diagnostics and Therapy, German Cancer Research Center, Im Neuenheimer Feld 280, D-69 120 Heidelberg, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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metabolism,
pathology* Brain Neoplasms / diagnosis, metabolism, therapy Central Nervous System Neoplasms / diagnosis*, metabolism, therapy Combined Modality Therapy Diagnosis, Differential Humans Image Enhancement Image Processing, Computer-Assisted Magnetic Resonance Imaging* Magnetic Resonance Spectroscopy Prognosis Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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