| Functional and morphological relationships between the feline main pancreatic and bile duct sphincters. | |
| | |
MedLine Citation:
|
PMID: 2105257 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To analyze the relationships between the bile duct and main pancreatic duct sphincters, the resistance to flow through these sphincters was studied simultaneously with perfusion techniques in anesthetized cats. Basal flow resistance was higher in the pancreatic sphincter than in the bile duct sphincter. The pressure in one duct system was not affected by the flow in the other. The muscular activities in the sphincters were usually well coordinated. Distention of the upper biliary tract or the pancreatic duct system reduced the flow resistance in both sphincters. Cholecystokinin-8 (0.01 micrograms), duodenal distention, and sublingual glyceryl trinitrate (0.4 mg) also relaxed both sphincters, whereas secretin in a dose that induced pancreatic secretion had no consistent effect. Morphine increased flow resistance in both systems. These functional studies indicate that the 2 sphincters share smooth muscle fibers at the level where the flow resistances arise, and there are thus no grounds for separate control of the sphincters. There was no evidence of a functionally common sphincter ampulla. The conclusions drawn from the manometric results were supported by morphological findings in this study. |
| | |
Authors:
|
A Thune; S Friman; N Conradi; J Svanvik |
Related Documents
:
|
20863267 - Lymphatic pump treatment increases thoracic duct lymph flow in conscious dogs with edem... 6139027 - Does the autonomic nervous system regulate whole-body lymph flow? 14607647 - Early intrajejunal nutrition: bacterial translocation and gut barrier function of sever... 1876597 - The effect of dopamine in a model of biliary acute hemorrhagic pancreatitis. 4053637 - Echocardiographic observations during cardiopulmonary resuscitation: a preliminary report. 6372877 - Effect of four primary prostaglandins and relaxin on blood flow in the ovine endometriu... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Gastroenterology Volume: 98 ISSN: 0016-5085 ISO Abbreviation: Gastroenterology Publication Date: 1990 Mar |
Date Detail:
|
Created Date: 1990-03-14 Completed Date: 1990-03-14 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0374630 Medline TA: Gastroenterology Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 758-65 Citation Subset: AIM; IM |
Affiliation:
|
Department of Surgery, University of Göteborg, Sahlgrenska Hospital, Gothenburg, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Biophysical Phenomena Biophysics Cats Cholecystokinin / pharmacology Common Bile Duct / anatomy & histology, drug effects, physiology* Morphine / pharmacology Nitroglycerin / pharmacology Pancreatic Ducts / anatomy & histology, drug effects, physiology* Secretin / pharmacology Sphincter of Oddi / anatomy & histology, drug effects, physiology |
| Chemical | |
Reg. No./Substance:
|
1393-25-5/Secretin; 55-63-0/Nitroglycerin; 57-27-2/Morphine; 9011-97-6/Cholecystokinin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of total enteral nutrition on the short-term outcome of severely malnourished cirrhotics. A r...
Next Document: Effects of ponalrestat on depressor responses to arachidonic acid in streptozotocin-diabetic rats.