| Functional and morphological recovery of the T-cell compartment in lethally irradiated and reconstituted mice. | |
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MedLine Citation:
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PMID: 381174 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The recovery of the T-cell compartment in mice after lethal irradiation and reconstitution was studied using functional and morphological parameters. T-helper cell activity, determined by the direct SRBC-plaque-forming cell (PFC) response, recovers in a similar fashion as T-memory function which was studied by adoptive transfer of carrier-primed cells. Both functions return to control levels in 2.5-3 months. Using immunoperoxidase staining of frozen sections with anti-T cell serum, the morphological recovery of the T-cell dependent areas in the white pulp of the spleen could be studied and compared with the functional recovery. |
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Authors:
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G Kraal; B van der Hilst; D Boden |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Immunology Volume: 37 ISSN: 0019-2805 ISO Abbreviation: Immunology Publication Date: 1979 May |
Date Detail:
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Created Date: 1979-10-17 Completed Date: 1979-10-17 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0374672 Medline TA: Immunology Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 195-201 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antilymphocyte Serum Hemolytic Plaque Technique Immunization, Passive Immunoenzyme Techniques Immunologic Memory Mice Spleen / pathology T-Lymphocytes / immunology*, pathology, radiation effects |
| Chemical | |
Reg. No./Substance:
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0/Antilymphocyte Serum |
| Comments/Corrections | |
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