Document Detail

Functional mitral regurgitation: modern concepts for ventricular geometry reshaping.
MedLine Citation:
PMID:  22404774     Owner:  NLM     Status:  In-Data-Review    
Functional mitral valve regurgitation (MR), a condition affecting millions of primarily elderly patients worldwide, is associated with poor clinical outcomes. Functional MR has traditionally been considered a disorder of regional or global left ventricular (LV) remodeling secondary to myocardial disease, in which anatomically normal leaflets fail to coapt adequately. The primary mechanisms of MR are mitral annular dilatation and leaflet restriction secondary to LV remodeling. Although annuloplasty is commonly used to correct valve incompetence, the effects of altered ventricular mechanics on MR need to be specifically addressed. This review focuses on current concepts of geometric reconfiguration of the LV and mitral-ventricular apparatus to reduce MR.
Jamshid H Karimov; Mariko Kobayashi; Kiyotaka Fukamachi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of medical devices     Volume:  9     ISSN:  1745-2422     ISO Abbreviation:  Expert Rev Med Devices     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230445     Medline TA:  Expert Rev Med Devices     Country:  England    
Other Details:
Languages:  eng     Pagination:  131-8     Citation Subset:  IM    
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
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