Document Detail


Functional mitral regurgitation From normal to pathological anatomy of mitral valve.
MedLine Citation:
PMID:  22192280     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Mitral valve (MV) is composed of several structures working in synchrony to open during diastole and close in systole within the high-pressure systemic environment. Its morphological features ensure a normal leaflet closure that prevents regurgitation of blood back into the left atrium causing loss of ventricular pressure and forward flow. The complex interactions of the normal MV are reliant on each component playing a complete role for the efficient working of the valve. In this review we firstly discuss the overall MV structure in terms of a complex make up of the annulus, the leaflets, their tendinous cords, and the supporting papillary muscles, and then the anatomical changes of each MV components due to left ventricular geometry and function alterations, underlying functional mitral regurgitation.
Authors:
Michele Di Mauro; Sabina Gallina; Maria Angela D'Amico; Pascal Izzicupo; Paola Lanuti; Adriana Bascelli; Alessia Di Fonso; Giovanni Bartoloni; Antonio Maria Calafiore; Angela Di Baldassarre;
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-20
Journal Detail:
Title:  International journal of cardiology     Volume:  -     ISSN:  1874-1754     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Dept. of Neuroscience and Imaging, University "G. D'Annunzio", Chieti, Pescara, Italy.
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