Document Detail


Functional magnetic resonance imaging of the liver: parametric assessments beyond morphology.
MedLine Citation:
PMID:  21094456     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
There is growing interest in exploring and using functional imaging techniques to provide additional information on structural alterations in the liver, which often occur late in the disease process. This article presents a summary of the different functional MR imaging techniques currently in use, focusing on dynamic contrast-enhanced MR imaging, diffusion-weighted MR imaging, MR spectroscopy, in- and oppose-phase MR imaging, and T2*-weighted imaging. For each technique, the biologic underpinning for the technique is explained, the clinical applications surveyed, and the challenges for their application enumerated. Developing and less frequently used techniques such as MR elastography, blood oxygenation level dependent imaging, dynamic susceptibility contrast-enhanced MR imaging, and diffusion-tensor imaging are reviewed. The challenges widespread adoption of functional MR imaging and the translation of such techniques to high field strengths are also discussed.
Authors:
Dow-Mu Koh; Anwar R Padhani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Magnetic resonance imaging clinics of North America     Volume:  18     ISSN:  1557-9786     ISO Abbreviation:  Magn Reson Imaging Clin N Am     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9422762     Medline TA:  Magn Reson Imaging Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  565-85, xii     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Radiology, Royal Marsden Hospital, Downs Road, Sutton SM2 5PT, UK. dmkoh@btinternet.com
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