| Functional inhibition of the human middle temporal cortex affects non-visual motion perception: a repetitive transcranial magnetic stimulation study during tactile speed discrimination. | |
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MedLine Citation:
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PMID: 21321310 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The visual motion-responsive middle temporal complex (hMT+) is activated during tactile and aural motion discrimination in both sighted and congenitally blind individuals, suggesting a supramodal organization of this area. Specifically, non-visual motion processing has been found to activate the more anterior portion of the hMT+. In the present study, repetitive transcranial magnetic stimulation (rTMS) was used to determine whether this more anterior portion of hMT+ truly plays a functional role in tactile motion processing. Sixteen blindfolded, young, healthy volunteers were asked to detect changes in the rotation velocity of a random Braille-like dot pattern by using the index or middle finger of their right hand. rTMS was applied for 600 ms (10 Hz, 110% motor threshold), 200 ms after the stimulus onset with a figure-of-eight coil over either the anterior portion of hMT+ or a midline parieto-occipital site (as a control). Accuracy and reaction times were significantly impaired only when TMS was applied on hMT+, but not on the control area. These results indicate that the recruitment of hMT+ is necessary for tactile motion processing, and thus corroborate the hypothesis of a 'supramodal' functional organization for this sensory motion processing area. |
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Authors:
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Emiliano Ricciardi; Demis Basso; Lorenzo Sani; Daniela Bonino; Tomaso Vecchi; Pietro Pietrini; Carlo Miniussi |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Experimental biology and medicine (Maywood, N.J.) Volume: 236 ISSN: 1535-3699 ISO Abbreviation: Exp. Biol. Med. (Maywood) Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100973463 Medline TA: Exp Biol Med (Maywood) Country: England |
Other Details:
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Languages: eng Pagination: 138-44 Citation Subset: IM |
Affiliation:
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Laboratory of Clinical Biochemistry and Molecular Biology, Department of Experimental Pathology, BMIE, University of Pisa Medical School, 56126 Pisa. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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