| Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging. | |
| | |
MedLine Citation:
|
PMID: 15547316 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Aging is associated with mitochondrial dysfunctions, which trigger membrane leakage, release of reactive species from oxygen and nitrogen and subsequent induction of peroxidative reactions that result in biomolecules' damaging and releasing of metals with amplification of free radicals discharge. Free radicals induce neuronal cell death increasing tissue loss, which could be associated with memory detriment. These pathological events are involved in cardiovascular, neurodegenerative and carcinogenic processes. Dietary bioactive compounds from different functional foods, herbs and nutraceuticals (ginseng, ginkgo, nuts, grains, tomato, soy phytoestrogens, curcumin, melatonin, polyphenols, antioxidant vitamins, carnitine, carnosine, ubiquinone, etc.) can ameliorate or even prevent diseases. Protection from chronic diseases of aging involves antioxidant activities, mitochondrial stabilizing functions, metal chelating activities, inhibition of apoptosis of vital cells, and induction of cancer cell apoptosis. Functional foods and nutraceuticals constitute a great promise to improve health and prevent aging-related chronic diseases. |
| | |
Authors:
|
Carlos K B Ferrari |
Related Documents
:
|
12202746 - Serotonin mediates food-odor associative learning in the nematode caenorhabditiselegans. 22152216 - Lack of effect of high-protein vs. high-carbohydrate meal intake on stress-related mood... 12381016 - Selective inspection planning with ageing forecast for sewer types. 23411326 - Tea polysaccharides as food antioxidants: an old woman's tale? 19339396 - Serum 25-hydroxyvitamin d status of vegetarians, partial vegetarians, and nonvegetarian... 11191806 - Current strategies for improving food bacteria. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Biogerontology Volume: 5 ISSN: 1389-5729 ISO Abbreviation: Biogerontology Publication Date: 2004 |
Date Detail:
|
Created Date: 2004-11-19 Completed Date: 2005-04-21 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 100930043 Medline TA: Biogerontology Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 275-89 Citation Subset: IM |
Affiliation:
|
Department of Nutrition, Faculty of Public Health, University of São Paulo, Av Dr. Arnaldo, 715, 2 andar, 01246-904, São Paulo (SP), Brazil. drcarlosferrari@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aging
/
physiology* Antioxidants / pharmacology Chelating Agents / pharmacology Food* Heart Diseases / prevention & control Herbal Medicine* Homocysteine / metabolism Humans Lipoproteins, LDL / metabolism Mitochondrial Diseases / physiopathology Oxidative Stress |
| Chemical | |
Reg. No./Substance:
|
0/Antioxidants; 0/Chelating Agents; 0/Lipoproteins, LDL; 454-28-4/Homocysteine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diagnosis of acute respiratory failure and nosocomial pneumonia
Next Document: Single nucleotide polymorphisms: aging and diseases.