Document Detail


Functional and evolutionary insights into the simple yet specific gut microbiota of the honey bee from metagenomic analysis.
MedLine Citation:
PMID:  23060052     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The honey bee, Apis mellifera, harbors a characteristic gut microbiota composed of only a few species which seem to be specific to social bees. The maintenance of this stable and distinct microbial community depends on the social lifestyle of these insects. As in other animals, the bacteria in the gut of honey bees probably govern important functions critical to host health. We recently sequenced a metagenome of the gut microbiota of A. mellifera, assigned gene contents to bins corresponding to the major species present in the honey bee gut, and compared functional gene categories between these species, and between the complete metagenome and those of other animals. Gene contents could be linked to different symbiotic functions with the host. Further, we found a high degree of genetic diversity within each of these species. In the case of the gammaproteobacterial species Gilliamella apicola, we experimentally showed a link between genetic variation of isolates and functional differences suggesting that niche partitioning within this species has emerged during evolution with its bee hosts. The consistent presence of only a few species, combined with strain variation within each of these species, makes the gut microbiota of social bees an ideal model for studying functional, structural, and evolutionary aspects of host-associated microbial communities: many characteristics resemble the gut microbiota of humans and other mammals, but the complexity is considerably reduced. In this addendum, we summarize and discuss our major findings and provide a detailed perspective on future research.
Authors:
Philipp Engel; Nancy A Moran
Publication Detail:
Type:  Journal Article; Review     Date:  2012-10-12
Journal Detail:
Title:  Gut microbes     Volume:  4     ISSN:  1949-0984     ISO Abbreviation:  Gut Microbes     Publication Date:    2013 Jan-Feb
Date Detail:
Created Date:  2013-01-24     Completed Date:  2013-07-03     Revised Date:  2014-01-09    
Medline Journal Info:
Nlm Unique ID:  101495343     Medline TA:  Gut Microbes     Country:  United States    
Other Details:
Languages:  eng     Pagination:  60-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bacteria / genetics
Bacterial Physiological Phenomena
Bees / microbiology*
Biota*
Gastrointestinal Tract / microbiology
Metagenome*
Symbiosis
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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