Document Detail


Functional endoscopic sinus surgery in the treatment of massive polyposis in asthmatic patients.
MedLine Citation:
PMID:  11893259     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The association between asthma and sinonasal disease has been known for years. Effective treatment of sinonasal disease, which is one of the factors that exacerbate asthma, may also improve and stabilize the asthmatic condition. This study examines the outcome of functional endoscopic sinus surgery (FESS) on asthmatic patients with massive nasal polyposis. Thirty-four asthmatic patients were included in the study. All were operated on in our department and were analysed for pre-operative data regarding their asthma and sinonasal disease. A questionnaire regarding subjective evaluation of asthma and sinonasal status was presented to the patients, and objective evaluations, including nasal endoscopy and spirometry, were performed. Follow-up endoscopy revealed satisfactory results in 88 per cent, with positive correlation to the patients' subjective assessment of nasal status. No such correlation was found with regard to subjective and objective assessment of asthma: a small group of patients had completely clean sinonasal cavities with no perceived improvement in their asthmatic condition. The use of prednisolone and bronchodilators was significantly reduced post-operatively. However, in a subgroup of 13 patients followed at the asthma clinic, who had adequate pre-operative and post-operative data, there was no difference in their pre- and post-operative asthma condition. Seven had minimal improvement and in six there was a definite worsening of their asthma; nevertheless, nasal breathing and quality of life improved in most patients. The mean follow-up was 2.1 years. Thus, we conclude that in this study FESS does not improve asthma, but does improve the quality of the life of the patient.
Authors:
Nechama Uri; Raanan Cohen-Kerem; Geva Barzilai; Elhanan Greenberg; Ilana Doweck; Daniel Weiler-Ravell
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  116     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-03-14     Completed Date:  2002-04-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  185-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Carmel Medical Center, Haifa, Israel. druri@netvision.net.il
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Airway Obstruction / complications,  surgery
Asthma / complications*,  drug therapy
Bronchodilator Agents / administration & dosage
Drug Administration Schedule
Endoscopy / methods
Female
Follow-Up Studies
Glucocorticoids / administration & dosage
Humans
Male
Middle Aged
Nasal Polyps / complications,  surgery*
Otorhinolaryngologic Surgical Procedures / methods
Postoperative Period
Prednisolone / administration & dosage
Quality of Life
Severity of Illness Index
Treatment Outcome
Chemical
Reg. No./Substance:
0/Bronchodilator Agents; 0/Glucocorticoids; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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