| Functional consequences of the glycophenotype of squamous epithelia--practical employment. | |
MedLine Citation:
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PMID: 12859021 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Squamous epithelia represent a morphologically and differentiation-dependent stratified tissue. The stem cells are located in the bulge region of hair follicles or in the basal layer of interfollicular epidermis and in the limbus of the cornea. This article summarizes the data about the glycobiological aspects of squamous epithelia cell differentiation under physiological as well as pathological conditions in relation to the function of this epithelial tissue. The entries about the LC, Merkel cells and melanocytes are also mentioned. The employment of the described data in the diagnostics of carcinomas derived from this type of epithelium as well as in the cell therapy of skin defects are shown. |
Authors:
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K Smetana; J Plzák; B Dvoránková; Z Holíková |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Folia biologica Volume: 49 ISSN: 0015-5500 ISO Abbreviation: Folia Biol. (Praha) Publication Date: 2003 |
Date Detail:
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Created Date: 2003-07-15 Completed Date: 2004-03-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0234640 Medline TA: Folia Biol (Praha) Country: Czech Republic |
Other Details:
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Languages: eng Pagination: 118-27 Citation Subset: IM |
Affiliation:
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Charles University, 1st Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic. Ksmet@1fl.cuni.cz |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Agglutinins
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chemistry Animals Carcinoma / metabolism Cell Differentiation Concanavalin A / pharmacology Epidermis / cytology Epithelium / pathology* Humans Islets of Langerhans / cytology Lectins Melanocytes / metabolism Merkel Cells / metabolism Models, Biological Phenotype Skin / pathology |
| Chemical | |
Reg. No./Substance:
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0/Agglutinins; 0/Lectins; 11028-71-0/Concanavalin A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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