Document Detail


Functional consequences of the glycophenotype of squamous epithelia--practical employment.
MedLine Citation:
PMID:  12859021     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Squamous epithelia represent a morphologically and differentiation-dependent stratified tissue. The stem cells are located in the bulge region of hair follicles or in the basal layer of interfollicular epidermis and in the limbus of the cornea. This article summarizes the data about the glycobiological aspects of squamous epithelia cell differentiation under physiological as well as pathological conditions in relation to the function of this epithelial tissue. The entries about the LC, Merkel cells and melanocytes are also mentioned. The employment of the described data in the diagnostics of carcinomas derived from this type of epithelium as well as in the cell therapy of skin defects are shown.
Authors:
K Smetana; J Plzák; B Dvoránková; Z Holíková
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Folia biologica     Volume:  49     ISSN:  0015-5500     ISO Abbreviation:  Folia Biol. (Praha)     Publication Date:  2003  
Date Detail:
Created Date:  2003-07-15     Completed Date:  2004-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0234640     Medline TA:  Folia Biol (Praha)     Country:  Czech Republic    
Other Details:
Languages:  eng     Pagination:  118-27     Citation Subset:  IM    
Affiliation:
Charles University, 1st Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic. Ksmet@1fl.cuni.cz
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MeSH Terms
Descriptor/Qualifier:
Agglutinins / chemistry
Animals
Carcinoma / metabolism
Cell Differentiation
Concanavalin A / pharmacology
Epidermis / cytology
Epithelium / pathology*
Humans
Islets of Langerhans / cytology
Lectins
Melanocytes / metabolism
Merkel Cells / metabolism
Models, Biological
Phenotype
Skin / pathology
Chemical
Reg. No./Substance:
0/Agglutinins; 0/Lectins; 11028-71-0/Concanavalin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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