| Functional cardiac MR imaging with steady-state free precession (SSFP) significantly improves endocardial border delineation without contrast agents. | |
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MedLine Citation:
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PMID: 11599059 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Contrast between blood and myocardium in standard turbo gradient echo MR techniques (TFE) used routinely in clinical practice is mainly caused by unsaturated inflowing blood. Steady-state free precession (SSFP) has excellent contrast even in the absence of inflow effects. In 45 subjects cardiac cine loops in two long axis projections were acquired using TFE and compared with SSFP. A visual score (range 0 worst - 3 best) was assigned for endocardial border delineation for six myocardial segments in two long axis views. Endocardial border delineation score for TFE was 1.3 +/- 0.3 per segment and 2.4 +/- 0.3 for SSFP (P < 0.0001). Signal intensity blood/signal intensity myocardium was 1.5 +/- 0.4 at enddiastole and 1.4 +/- 0.3 at systole for TFE and 3.5 +/- 1.1 and 3.2 +/- 1.3 for SSFP, respectively (P < 0.0001). SSFP increases contrast between blood and myocardium more than twofold, resulting in an improved endocardial border definition. This may reduce variability for the determination of cardiac volumes and ejection fraction. |
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Authors:
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H Thiele; E Nagel; I Paetsch; B Schnackenburg; A Bornstedt; M Kouwenhoven; A Wahl; G Schuler; E Fleck |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 14 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-10-12 Completed Date: 2001-12-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 362-7 Citation Subset: IM |
Copyright Information:
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Copyright 2001 Wiley-Liss, Inc. |
Affiliation:
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Clinic of Internal Medicine/Cardiology, University of Leipzig, Heart Center Leipzig, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Cardiac Volume Endocardium / anatomy & histology* Humans Magnetic Resonance Imaging / methods* Middle Aged Stroke Volume |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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