Document Detail

Functional Performance and Inflammatory Cytokines after Squat Exercises and Whole-Body Vibration in Elderly Individuals With Knee Osteoarthritis.
MedLine Citation:
PMID:  22546535     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To investigate the effects of squat exercises combined with whole-body vibration on the plasma concentration of inflammatory markers and the functional performance of elderly individuals with knee osteoarthritis. DESIGN: Clinical, prospective, randomized, single-blinded study. SETTING: Exercise Physiology Laboratory. PARTICIPANTS: Thirty-two elderly subjects with knee osteoarthritis were divided into three groups [i.e., squat exercises on a vibratory platform (platform group N= 11), squat exercises without vibration (squat group N= 10) and the control group (N=11)]. INTERVENTIONS: The structured program of squat exercises in the platform and squat groups was conducted three times per week, on alternate days, for 12 weeks. MAIN OUTCOME MEASURES: Plasma sTNFR1 and sTNFR2 were measured using immunoassays (the ELISA method). The Western Ontario and McMaster University Osteoarthritis Index (WOMAC) questionnaire was used to evaluate self-reported physical function, pain and stiffness. The 6-minute walk test, the Berg balance scale, and gait speed were used to evaluate physical function. RESULTS: In the group that performed squat exercises on a vibratory platform, there were significant reductions in the plasma concentrations of the inflammatory markers sTNFR1 and sTNFR2 (p<0.001 and p<0.05, respectively) and self-reported pain (p<0.05) compared with the control group; however, there was an increase in balance (p<0.05) and speed and distance walked (p<0.05 and p<0.001, respectively). In addition, the group that performed squat exercises on a vibratory platform walked faster than the group that only performed squat exercises (p<0.01). CONCLUSION: The results suggest that whole-body vibration training improves self-perception of pain, balance, gait quality and inflammatory markers in elderly subjects with knee osteoarthritis.
Adriano P Simão; Núbia C Avelar; Rosalina Tossige-Gomes; Camila D Neves; Vanessa A Mendonça; Aline S Miranda; Mauro M Teixeira; Antônio L Teixeira; André P Andrade; Cândido C Coimbra; Ana Cristina R Lacerda
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-27
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  -     ISSN:  1532-821X     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-5-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 the American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Exercise Physiology Laboratory, School of Health and Biological Sciences, Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, MG; Multicenter Post Graduation Program in Physiological Sciences, Brazilian Society of Physiology, Brazil.
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